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The HOMO-LUMO distribution in Ecdysterone is illustrated in Fig 5C the place the pink and blue isosurfaces characterize negatively and positively charged sites. An appropriately massive HOMO-LUMO energy gap （E） of two.37 eV indicates the kinetic stability of this molecule while the presence of HOMO and LUMO isosurfaces on the same website of the molecule exhibits low intramolecular cost transfer. The ERα in complex with Estradiol （Fig 3A） established multiple sources of interaction including hydrogen bonding and hydrophobic interplay and likely dipole-dipole interactions between polar groups. The oral bioavailability of AAS could be increased by making the parent molecule more lipid-soluble by the esterification process described in the previous paragraph. This modification permits a bigger fraction of the absorbed AAS to enter the lymphatic system and bypass first-pass me Nevertheless even after esterification of testosterone by an 11-carbon carboxylic acid group （undecanoate） oral bio |
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时间: 06-06 17:49
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Nonetheless because of methyltrienolone’s high toxicity even in modest dosages bodybuilders hardly use it and prefer injectable trenbolone instead. Our patients’ liver function exams and blood pressure readings indicate methyltrienolone to be unsafe. Anecdotally we also see it cause disturbances to the central nervous system thus negatively influencing temper and well-being comparable to leisure drugs such as amphetamine or cocaine. Although some anabolic steroids are FDA-approved corresponding to testosterone they‘ll only be legally obtained via a presc Dianabol should by no means be taken with another hepatotoxic oral steroid （such as Anadrol Superdrol or Winstrol）. We have treated advanced steroid users taking dosages as high as a hundred mg/day and operating Anadrol cycles for as a lot as 8 weeks. Greatest of all there’s no testost |
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